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Additional Instructions for Patients

MAKE SURE YOUR PATIENT KNOWS:

VELTASSA can be taken with or without food.

  • DO adhere to recommended diet
  • DO mix VELTASSA with water, juice, or soft food in separate steps to avoid clumping
  • DO NOT take other oral drugs less than 3 hours before or after taking VELTASSA to avoid possible interaction
  • DO NOT heat VELTASSA or add to heated foods or liquids
  • DO NOT mix VELTASSA in a blender
  • DO NOT take in dry form

Help your patients remember their once-daily treatment—suggest they create a refill plan, set calendar reminders, or ask a loved one to remind them.

ITEMS YOUR PATIENTS WILL NEED TO TAKE VELTASSA:

Packet

VELTASSA PACKET

Scissors

SCISSORS

Glass

GLASS

Cup

1/3 CUP OF WATER

Spoon

SPOON

Juice and soft foods, such as applesauce, yogurt, and pudding, can be used instead of water to prepare the mixture.

VELTASSA support for your practice and patients

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INDICATION

VELTASSA is indicated for the treatment of hyperkalemia.

Limitation of Use: VELTASSA should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action.

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INDICATION & Important Safety Information

Important Safety Information

VELTASSA is indicated for the treatment of hyperkalemia.

Limitation of Use: VELTASSA should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action.

CONTRAINDICATIONS

VELTASSA is contraindicated in patients with a history of a hypersensitivity reaction to VELTASSA or any of its components.

INDICATION

VELTASSA is indicated for the treatment of hyperkalemia.

Limitation of Use: VELTASSA should not be used as an emergency treatment for life-threatening hyperkalemia because of its delayed onset of action.

IMPORTANT SAFETY INFORMATION

CONTRAINDICATIONS

VELTASSA is contraindicated in patients with a history of a hypersensitivity reaction to VELTASSA or any of its components.

WARNINGS AND PRECAUTIONS

Worsening of Gastrointestinal Motility: Avoid use of VELTASSA in patients with severe constipation, bowel obstruction or impaction, including abnormal post-operative bowel motility disorders, because VELTASSA may be ineffective and may worsen gastrointestinal conditions. Patients with a history of bowel obstruction or major gastrointestinal surgery, severe gastrointestinal disorders, or swallowing disorders were not included in clinical studies.

Hypomagnecemia: VELTASSA binds to magnesium in the colon, which can lead to hypomagnecemia. In clinical studies, hypomagnecemia was reported as an adverse reaction in 5.3% of patients treated with VELTASSA. Approximately 9% of patients in clinical trials developed hypomagnecemia with a serum magnesium value <1.4 mg/dL. Monitor serum magnesium. Consider magnesium supplementation in patients who develop low serum magnesium levels.

MOST COMMON ADVERSE REACTIONS

The most common adverse reactions (incidence ≥2%) were constipation (7.2%), hypomagnecemia (5.3%), diarrhea (4.8%), nausea (2.3%), abdominal discomfort (2.0%) and flatulence (2.0%). Mild to moderate hypersensitivity reactions were reported in 0.3% of patients treated with VELTASSA and included edema of the lips.